Buffalo Chicken Sub Recipe
Meet the perfect party sandwich no one can resist — the Buffalo chicken sub! This spicy chicken sandwich takes less than 30 minutes to prepare and features shredded Buffalo chicken, gooey mozzarella, a drizzle of ranch dressing and tangy blue cheese crumbles, all on a toasted, buttery bun.

How to Make the Best Buffalo Chicken Sub
This buffalo chicken sub is the ultimate crowd-pleaser that brings bold, spicy flavors to your table in less than 30 minutes. The combination of tangy Frank’s RedHot Sauce, creamy mozzarella, and cool ranch dressing creates the perfect balance of heat and comfort. Whether you’re hosting a casual gathering, planning for game day, or need a quick dinner solution, this sandwich delivers impressive results with minimal effort.
Why This Recipe Works
The magic of this buffalo chicken sub lies in its simplicity and balance of flavors. By tossing shredded chicken directly in the Buffalo sauce before assembling, you ensure every bite is infused with that signature spicy kick. The oven does most of the work for you—the bread toasts to golden perfection while the mozzarella melts into gooey goodness, creating layers of texture and flavor that make this sandwich irresistible.
Serving Suggestions
Serve these subs alongside crisp celery sticks with a blue cheese dipping sauce, classic French fries, or a fresh green salad. The cool, creamy toppings of ranch dressing and blue cheese crumbles help tame the heat of the Buffalo sauce, making this sandwich accessible to any heat tolerance level. With just 346 calories per serving, you can enjoy this indulgent sandwich without the guilt.

Buffalo Chicken Sub
Meet the perfect party sandwich no one can resist — the Buffalo chicken sub! This spicy chicken sandwich takes less than 30 minutes to prepare and features shredded Buffalo chicken, gooey mozzarella, a drizzle of ranch dressing and tangy blue cheese crumbles, all on a toasted, buttery bun.
Ingredients
Buffalo Chicken
Assembly
Instructions
Prepare the Sauce
- Turn the oven to 375 degrees. Heat the Frank's RedHot Sauce and 4 tablespoons butter together, reserving 2 tablespoons butter. Stir together to make one cohesive Buffalo sauce.
Cook the Chicken
- Toss together the Buffalo sauce and chicken until well coated.
Assemble and Bake
- Divide the chicken evenly to fill the hoagie or split French rolls and top with mozzarella. If your roll is completely split into two, top with the other half of the bread and place the subs in a baking pan. Cover the baking pan with foil.
- Bake until the subs are heated through and the cheese melts, about 15 minutes. Remove the foil and bake for another three minutes to toast the bread.
- As the subs bake, heat the remaining 2 tablespoons butter. When the subs finish baking, brush the bread with the melted butter. Enjoy!
Notes
- This recipe makes 4 large subs, perfect for serving at a gathering or game day party.
- Prep time is minimal—less than 30 minutes total from start to finish.